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Index > Protein center > Fasn(Gene name) > Rat
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  • Fasn (Gene name),
  • Fatty acid synthase (Protein name ),  FAS_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Fasn;
    Protein name:
    Fatty acid synthase;
    Alternative:

    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Homodimer which is arranged in a head to tail fashion.
    Function:
    Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities and an acyl carrier protein.
    Subcellular Location:
    Cytoplasm Melanosome
    Protein Attributes:
    Sequence length:
    2505
    Sequence:
    50:
    MEEVVIAGMS | GKLPESENLQ | EFWANLIGGV | DMVTDDDRRW | KAGLYGLPKR | 
    100:
    SGKLKDLSKF | DASFFGVHPK | QAHTMDPQLR | LLLEVSYEAI | VDGGINPASL | 
    150:
    RGTNTGVWVG | VSGSEASEAL | SRDPETLLGY | SMVGCQRAMM | ANRLSFFFDF | 
    200:
    KGPSIALDTA | CSSSLLALQN | AYQAIRSGEC | PAAIVGGINL | LLKPNTSVQF | 
    250:
    MKLGMLSPDG | TCRSFDDSGN | GYCRAEAVVA | VLLTKKSLAR | RVYATILNAG | 
    300:
    TNTDGCKEQG | VTFPSGEAQE | QLIRSLYQPG | GVAPESLEYI | EAHGTGTKVG | 
    350:
    DPQELNGITR | SLCAFRQSPL | LIGSTKSNMG | HPEPASGLAA | LTKVLLSLEN | 
    400:
    GVWAPNLHFH | NPNPEIPALL | DGRLQVVDRP | LPVRGGIVGI | NSFGFGGANV | 
    450:
    HVILQPNTQQ | APAPAPHAAL | PHLLHASGRT | MEAVQGLLEQ | GRQHSQDLAF | 
    500:
    VSMLNDIAAT | PTAAMPFRGY | TVLGVEGHVQ | EVQQVPASQR | PLWFICSGMG | 
    550:
    TQWRGMGLSL | MRLDSFRESI | LRSDEALKPL | GVKVSDLLLS | TDEHTFDDIV | 
    600:
    HSFVSLTAIQ | IALIDLLTSM | GLKPDGIIGH | SLGEVACGYA | DGCLSQREAV | 
    650:
    LAAYWRGQCI | KDANLPAGSM | AAVGLSWEEC | KQRCPPGVVP | ACHNSEDTVT | 
    700:
    ISGPQAAVNE | FVEQLKQEGV | FAKEVRTGGL | AFHSYFMEGI | APTLLQALKK | 
    750:
    VIREPRPRSA | RWLSTSIPEA | QWQSSLARTS | SAEYNVNNLV | SPVLFQEALW | 
    800:
    HVPEHAVVLE | IAPHALLQAV | LKRGVKPSCT | IIPLMKRDHK | DNLEFFLTNL | 
    850:
    GKVHLTGIDI | NPNALFPPVE | FPVPRGTPLI | SPHIKWDHSQ | TWDIPVAEDF | 
    900:
    PNGSSSSSAT | VYNIDASSES | SDHYLVDHCI | DGRVLFPGTG | YLYLVWKTLA | 
    950:
    RSLSLSLEET | PVVFENVTFH | QATILPRTGT | VPLEVRLLEA | SHAFEVSDSG | 
    1000:
    NLIVSGKVYQ | WEDPDSKLFD | HPEVPIPAES | ESVSRLTQGE | VYKELRLRGY | 
    1050:
    DYGPHFQGVY | EATLEGEQGK | LLWKDNWVTF | MDTMLQISIL | GFSKQSLQLP | 
    1100:
    TRVTAIYIDP | ATHLQKVYML | EGDTQVADVT | TSRCLGVTVS | GGVYISRLQT | 
    1150:
    TATSRRQQEQ | LVPTLEKFVF | TPHVEPECLS | ESAILQKELQ | LCKGLAKALQ | 
    1200:
    TKATQQGLKM | TVPGLEDLPQ | HGLPRLLAAA | CQLQLNGNLQ | LELGEVLARE | 
    1250:
    RLLLPEDPLI | SGLLNSQALK | ACIDTALENL | STLKMKVVEV | LAGEGHLYSH | 
    1300:
    ISALLNTQPM | LQLEYTATDR | HPQALKDVQT | KLQQHDVAQG | QWDPSGPAPT | 
    1350:
    NLGALDLVVC | NCALATLGDP | ALALDNMVAA | LKDGGFLLMH | TVLKGHALGE | 
    1400:
    TLACLPSEVQ | PGPSFLSQEE | WESLFSRKAL | HLVGLKKSFY | GTALFLCRRL | 
    1450:
    SPQDKPIFLP | VEDTSFQWVD | SLKSILATSS | SQPVWLTAMN | CPTSGVVGLV | 
    1500:
    NCLRKEPGGH | RIRCILLSNL | SSTSHVPKLD | PGSSELQKVL | ESDLVMNVYR | 
    1550:
    DGAWGAFRHF | QLEQDKPEEQ | TAHAFVNVLT | RGDLASIRWV | SSPLKHMQPP | 
    1600:
    SSSGAQLCTV | YYASLNFRDI | MLATGKLSPD | AIPGKWASRD | CMLGMEFSGR | 
    1650:
    DKCGRRVMGL | VPAEGLATSV | LLSPDFLWDV | PSSWTLEEAA | SVPVVYTTAY | 
    1700:
    YSLVVRGRIQ | HGETVLIHSG | SGGVGQAAIS | IALSLGCRVF | TTVGSAEKRA | 
    1750:
    YLQARFPQLD | DTSFANSRDT | SFEQHVLLHT | GGKGVDLVLN | SLAEEKLQAS | 
    1800:
    VRCLAQHGRF | LEIGKFDLSN | NHPLGMAIFL | KNVTFHGILL | DALFEGANDS | 
    1850:
    WREVAELLKA | GIRDGVVKPL | KCTVFPKAQV | EDAFRYMAQG | KHIGKVLVQV | 
    1900:
    REEEPEAMLP | GAQPTLISAI | SKTFCPEHKS | YIITGGLGGF | GLELARWLVL | 
    1950:
    RGAQRLVLTS | RSGIRTGYQA | KHVREWRRQG | IHVLVSTSNV | SSLEGARALI | 
    2000:
    AEATKLGPVG | GVFNLAMVLR | DAMLENQTPE | LFQDVNKPKY | NGTLNLDRAT | 
    2050:
    REACPELDYF | VAFSSVSCGR | GNAGQSNYGF | ANSTMERICE | QRRHDGLPGL | 
    2100:
    AVQWGAIGDV | GIILEAMGTN | DTVVGGTLPQ | RISSCMEVLD | LFLNQPHAVL | 
    2150:
    SSFVLAEKKA | VAHGDGEAQR | DLVKAVAHIL | GIRDLAGINL | DSSLADLGLD | 
    2200:
    SLMGVEVRQI | LEREHDLVLP | IREVRQLTLR | KLQEMSSKAG | SDTELAAPKS | 
    2250:
    KNDTSLKQAQ | LNLSILLVNP | EGPTLTRLNS | VQSSERPLFL | VHPIEGSITV | 
    2300:
    FHSLAAKLSV | PTYGLQCTQA | APLDSIPNLA | AYYIDCIKQV | QPEGPYRVAG | 
    2350:
    YSFGACVAFE | MCSQLQAQQG | PAPAHNNLFL | FDGSHTYVLA | YTQSYRAKLT | 
    2400:
    PGCEAEAEAE | AICFFIKQFV | DAEHSKVLEA | LLPLKSLEDR | VAAAVDLITR | 
    2450:
    SHQSLDRRDL | SFAAVSFYYK | LRAADQYKPK | AKYHGNVILL | RAKTGGTYGE | 
    2500:
    DLGADYNLSQ | VCDGKVSVHI | IEGDHRTLLE | GRGLESIINI | IHSSLAEPRV | 
    2505:
    SVREG
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    Pfam:
    SMR:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Fatty acid synthase
    Cat.:
    E1451m
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Rat Fatty acid synthase
    Cat.:
    E1451h
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Rat Fatty acid synthase
    Cat.:
    E1451r
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    Packing:
    96T
    ELISA Kit for Rat Fatty acid synthase
    Cat.:
    E1451b
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    Packing:
    96T
    ELISA Kit for Rat Fatty acid synthase
    Cat.:
    E1451c
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Rat Fatty acid synthase
    MSDS:
    Please sign in first.
    CLIA Kit for Rat Fatty acid synthase
    Cat.:
    U1451m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Fatty acid synthase
    Cat.:
    U1451r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Fatty acid synthase
    Cat.:
    U1451h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Fatty acid synthase
    Cat.:
    U1451c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Fatty acid synthase
    Cat.:
    U1451b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Fatty acid synthase
    MSDS:
    Please sign in first.
    Polyclonal Antibody for Rat Fatty acid synthase
    Cat.:
    P1451Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Fatty acid synthase
    Polyclonal Antibody for Rat Fatty acid synthase
    Cat.:
    P1451Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Fatty acid synthase
    Polyclonal Antibody for Rat Fatty acid synthase
    Cat.:
    P1451Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Fatty acid synthase
    Monoclonal Antibody for Rat Fatty acid synthase
    Monoclonal Antibody for Rat Fatty acid synthase
    Monoclonal Antibody for Rat Fatty acid synthase
    Monoclonal Antibody for Rat Fatty acid synthase
    Monoclonal Antibody for Rat Fatty acid synthase
    Monoclonal Antibody for Rat Fatty acid synthase
    Protein for Rat Fatty acid synthase
    Protein for Rat Fatty acid synthase
    Protein for Rat Fatty acid synthase
    Protein for Rat Fatty acid synthase
    Protein for Rat Fatty acid synthase
    Protein for Rat Fatty acid synthase

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Molecular cloning and sequencing of cDNAs encoding the entire rat fatty acid synthase."
      Amy C.M. , Witkowski A. , Naggert J. , Williams B. , Randhawa Z. , Smith S.
      Proc. Natl. Acad. Sci. U.S.A.86:3114-3118(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "The fatty acid synthase (FAS) gene and its promoter in Rattus norvegicus."
      Beck K.F. , Schreglmann R. , Stathopulos I. , Klein H. , Hoch J. , Schweizer M.
      DNA Seq.2:359-386(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]
      strain: Sprague-Dawley.
      tissue: Liver.
    3. 3.
      "Intron-exon organization of the gene for the multifunctional animal fatty acid synthase."
      Amy C.M. , Williams-Ahlf B. , Naggert J. , Smith S.
      Proc. Natl. Acad. Sci. U.S.A.89:1105-1108(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    4. 4.
      "Rat mammary gland fatty acid synthase: localization of the constituent domains and two functional polyadenylation/termination signals in the cDNA."
      Schweizer M. , Takabeyashi K. , Beck K.F. , Schreglmann R.
      Nucleic Acids Res.17:567-586(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 75-2505
      strain: Sprague-Dawley.
      tissue: Mammary gland.
    5. 5.
      "Molecular cloning and sequencing of a cDNA encoding the acyl carrier protein and its flanking domains in the mammalian fatty acid synthetase."
      Witlowski A. , Naggert J. , Mikkelsen J. , Smith S.
      Eur. J. Biochem.165:601-606(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1921-2324
      tissue: Mammary gland.
    6. 6.
      "Molecular cloning and sequencing of a cDNA encoding the thioesterase domain of the rat fatty acid synthetase."
      Naggert J. , Witkowski A. , Mikkelsen J. , Smith S.
      J. Biol. Chem.263:1146-1150(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 2085-2505
      tissue: Mammary gland.
    7. 7.
      "Nutritional control of rat liver fatty acid synthase and S14 mRNA abundance."
      Clarke S.D. , Armstrong M.K. , Jump D.B.
      J. Nutr.120:218-224(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE OF 2377-2413;INDUCTION
    8. 8.
      "The type I rat fatty acid synthase ACP shows structural homology and analogous biochemical properties to type II ACPs."
      Reed M.A.C. , Schweizer M. , Szafranska A.E. , Arthur C. , Nicholson T.P. , Cox R.J. , Crosby J. , Crump M.P. , Simpson T.J.
      Org. Biomol. Chem.1:463-471(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 2114-2202
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